Autoantibodies to oxidised low density lipoproteins in IDDM are inversely related to metabolic control and microvascular complications

@article{Festa1998AutoantibodiesTO,
  title={Autoantibodies to oxidised low density lipoproteins in IDDM are inversely related to metabolic control and microvascular complications},
  author={Andreas Festa and H. P. Kopp and Guntram Schernthaner and Ernst Johannes Menzel},
  journal={Diabetologia},
  year={1998},
  volume={41},
  pages={350-356}
}
Diabetes mellitus is associated with an increased risk of atherosclerosis. The oxidation of low-density lipoproteins (LDL) is considered a key event in the initiation of atherosclerosis. To investigate LDL oxidation in vivo we measured autoantibodies to oxidised LDL (oxLDL) in 94 patients with insulin-dependent diabetes mellitus (IDDM), compared to 27 age-matched, healthy control subjects. Patients and control subjects were screened for autoantibodies using a solid phase ELISA, comparing the… CONTINUE READING

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