Autoantibodies to nervous tissue structures are associated with autonomic neuropathy in Type 1 (insulin-dependent) diabetes mellitus

@article{Zanone1993AutoantibodiesTN,
  title={Autoantibodies to nervous tissue structures are associated with autonomic neuropathy in Type 1 (insulin-dependent) diabetes mellitus},
  author={Maria M. Zanone and Mark Peakman and Tarsem S. Purewal and Peter J. Watkins and Diego Vergani},
  journal={Diabetologia},
  year={1993},
  volume={36},
  pages={564-569}
}
There is evidence that the immune system may play a role in the pathogenesis of autonomic neuropathy in Type 1 (insulin-dependent) diabetes mellitus. In the present study, we investigated the presence of autoantibodies to sympathetic and parasympathetic nervous structures and their correlation with other conventional autoantibodies in well-characterised diabetic populations, with or without diabetic neuropathy, and normal subjects. An indirect immunofluorescent complement-fixation technique was… CONTINUE READING

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