Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis.

@article{Sato2005AutoantibodiesTA,
  title={Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis.},
  author={Shinji Sato and Michito Hirakata and Masataka Kuwana and Akira Suwa and Shinichi Inada and Tsuneyo Mimori and Takeji Nishikawa and Chester V. Oddis and Yasuo Ikeda},
  journal={Arthritis and rheumatism},
  year={2005},
  volume={52 5},
  pages={1571-6}
}
OBJECTIVE To identify novel autoantibodies specific for dermatomyositis (DM), especially those specific for clinically amyopathic DM (C-ADM). METHODS Autoantibodies were analyzed by immunoprecipitation in 298 serum samples from patients with various connective tissue diseases (CTDs) or idiopathic pulmonary fibrosis (IPF). Antigen specificity of the sera was further examined by immunoblotting and indirect immunofluorescence (IF). The disease specificity and clinical features associated with… CONTINUE READING