Autoantibodies to IL-17A may be Correlated with the Severity of Mucocutaneous Candidiasis in APECED Patients

@article{Sarkadi2014AutoantibodiesTI,
  title={Autoantibodies to IL-17A may be Correlated with the Severity of Mucocutaneous Candidiasis in APECED Patients},
  author={Adrien Katalin Sarkadi and Szilvia Task{\'o} and Gabriella Csorba and Be{\'a}ta T{\'o}th and Melinda Erdős and L{\'a}szl{\'o} Mar{\'o}di},
  journal={Journal of Clinical Immunology},
  year={2014},
  volume={34},
  pages={181-193}
}
The relative roles of various autoantibodies against IL-17-type cytokines in susceptibility to chronic mucocutaneous candidiasis (CMC) in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) remain poorly defined. The purpose of this longitudinal study was to analyze the relationship between the occurrence of mucocutaneous candidiasis and levels of anti-IL-17A, anti-IL-17F and anti-IL-22 autoantibodies. We studied six APECED patients from four families with… CONTINUE READING

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