Autoantibodies in primary sclerosing cholangitis.

  title={Autoantibodies in primary sclerosing cholangitis.},
  author={Johannes-Roksund Hov and Kirsten-Muri Boberg and Tom H. Karlsen},
  journal={World journal of gastroenterology},
  volume={14 24},
The aetiology of primary sclerosing cholangitis (PSC) is not known and controversy exists as to whether PSC should be denominated an autoimmune disease. A large number of autoantibodies have been detected in PSC patients, but the specificity of these antibodies is generally low, and the frequencies vary largely between different studies. The presence of… CONTINUE READING