Autoantibodies in black South Africans with systemic lupus erythematosus: Spectrum and clinical associations

@article{Tikly1996AutoantibodiesIB,
  title={Autoantibodies in black South Africans with systemic lupus erythematosus: Spectrum and clinical associations},
  author={Mohammed Tikly and Susan Burgin and Paraskumar Mohanlal and A. Bellingan and Jacob George},
  journal={Clinical Rheumatology},
  year={1996},
  volume={15},
  pages={261-265}
}
The clinical features and autoantibody profile of 111 black South Africans (103 females and 8 males) with systemic lupus erythematosus were retrospectively analysed. The mean age of the patients was 35.1 years and mean duration of disease 3.5 years. The commonest clinical and laboratory features noted were arthritis (62.2%), hypocomplementaemia (61.2%), haematological abnormalities (60.5%) and malar rash (55%). The serological abnormalities included antinuclear antibodies (98.2%), anti-dsDNA… CONTINUE READING