Autoantibodies as predictors of disease

@article{Scofield2004AutoantibodiesAP,
  title={Autoantibodies as predictors of disease},
  author={Robert Hal Scofield},
  journal={The Lancet},
  year={2004},
  volume={363},
  pages={1544-1546}
}

2 Non-thyroid autoantibodies in autoimmune thyroid disease

TLDR
There are no large-scale trials that have shown the cost–benefit ratio of autoantibody screening for autoimmunity screening, and clinicians must use individual judgement combined with heightened awareness to identify who to test.

Non-thyroid autoantibodies in autoimmune thyroid disease.

  • A. Weetman
  • Medicine, Biology
    Best practice & research. Clinical endocrinology & metabolism
  • 2005

Prediction and prevention of autoimmune skin disorders

TLDR
Although large body of evidence has accumulated on characteristic autoantibodies, susceptible genes and environmental factors, many more large scale studies are needed to assess their predictive value, the preventive measurements and the means to apply them to clinical management of healthy population and high-risk individuals.

Prediction and prevention of autoimmune diseases: additional aspects of the mosaic of autoimmunity

TLDR
The aim of this article is to review the major risk factors for autoimmune disease, both hereditary and environmental, and so to help define those future criteria for preventive treatment.

Emerging relationships: rheumatoid arthritis and the PTPN22 associated autoimmune disorders

TLDR
The example of PTPN22 illustrates how human genetics is likely to provide new insights into pathogenesis and unravel new relationships among the autoimmune diseases.

Organ specific-autoantibodies: Their role as markers and predictors of disease

TLDR
The wide range of affected organ systems and the overlap between different diseases pose several clinical challenges, and some of the problems frequently encountered are assessment of risk.

On the Trail of Diseases, Years Before They Strike - Auto Antibodies

TLDR
The ability to predict auto immune diseases, or rather their clinical manifestations lead to the prospect of screening healthy individuals for auto antibodies, which will enable to prevent life threatening manifestations and help to treat or even prevent overt autoimmune diseases.

The diagnostic role of autoantibodies in the prediction of organ-specific autoimmune diseases

  • R. Tozzoli
  • Medicine, Biology
    Clinical chemistry and laboratory medicine
  • 2008
TLDR
This review examines the various autoantibodies of demonstrated predictive role in organ-specific autoimmune diseases and it introduces the state-of-the-art in the detection of multiple autoantIBodies with proteomic systems.

Studies on the role of autoantibodies and autoantigens in rheumatoid arthritis and myositis

TLDR
The aims of the thesis were to understand the molecular mechanisms underlying the autoimmune component (specifically, the auto-antibody and -antigen dynamics) in RA and myositis; and to develop ACPA neutralizing compounds.

Spectrum of Thyroid Disorders in Sero Positive Rheumatoid Arthritis

TLDR
Thyroid dysfunction is prevalent in patients with rheumatoid arthritis with percentage of 41.8%, subclinical hypothyroidism is the most common thyroid dysfunction encountered followed by overt hypothy thyroid dysfunction (3.6%), hyperthyroidistan is very rare seen only 0.3% patients.
...

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