Autoantibodies as predictors of disease

@article{Scofield2004AutoantibodiesAP,
  title={Autoantibodies as predictors of disease},
  author={Robert Hal Scofield},
  journal={The Lancet},
  year={2004},
  volume={363},
  pages={1544-1546}
}
2 Non-thyroid autoantibodies in autoimmune thyroid disease
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There are no large-scale trials that have shown the cost–benefit ratio of autoantibody screening for autoimmunity screening, and clinicians must use individual judgement combined with heightened awareness to identify who to test.
Non-thyroid autoantibodies in autoimmune thyroid disease.
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Optized, standardized and cost-effective multiparametric assays are the prerequisite for a probable future use of autoantibodies for the more accurate prediction of diseases.
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The aim of this article is to review the major risk factors for autoimmune disease, both hereditary and environmental, and so to help define those future criteria for preventive treatment.
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The example of PTPN22 illustrates how human genetics is likely to provide new insights into pathogenesis and unravel new relationships among the autoimmune diseases.
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The wide range of affected organ systems and the overlap between different diseases pose several clinical challenges, and some of the problems frequently encountered are assessment of risk.
On the Trail of Diseases, Years Before They Strike - Auto Antibodies
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The ability to predict auto immune diseases, or rather their clinical manifestations lead to the prospect of screening healthy individuals for auto antibodies, which will enable to prevent life threatening manifestations and help to treat or even prevent overt autoimmune diseases.
The diagnostic role of autoantibodies in the prediction of organ-specific autoimmune diseases
  • R. Tozzoli
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  • 2008
TLDR
This review examines the various autoantibodies of demonstrated predictive role in organ-specific autoimmune diseases and it introduces the state-of-the-art in the detection of multiple autoantIBodies with proteomic systems.
Studies on the role of autoantibodies and autoantigens in rheumatoid arthritis and myositis
TLDR
The aims of the thesis were to understand the molecular mechanisms underlying the autoimmune component (specifically, the auto-antibody and -antigen dynamics) in RA and myositis; and to develop ACPA neutralizing compounds.
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