Autoantibodies against thyroid hormones or iodothyronine. Implications in diagnosis, thyroid function, treatment, and pathogenesis.

@article{Sakata1985AutoantibodiesAT,
  title={Autoantibodies against thyroid hormones or iodothyronine. Implications in diagnosis, thyroid function, treatment, and pathogenesis.},
  author={Seiichiro Sakata and Shigenori Nakamura and Kiyoshi Miura},
  journal={Annals of internal medicine},
  year={1985},
  volume={103 4},
  pages={579-89}
}
The presence of antithyroid hormone autoantibodies in the sera of patients with thyroid and nonthyroid disorders is a well-known condition. When circulating thyroid hormones bind to the patients' immunoglobulins, serum levels of total and free thyroid hormones are often in discordance with clinical features. This problem occurs because the autoantibodies can interfere with radioimmunoassays. To avoid inappropriate treatment of such patients, it is clinically important to consider the presence… CONTINUE READING

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