Autoantibodies against soluble and immobilized human recombinant tissue transglutaminase in children with celiac disease.

@article{Agardh2005AutoantibodiesAS,
  title={Autoantibodies against soluble and immobilized human recombinant tissue transglutaminase in children with celiac disease.},
  author={Daniel Agardh and Ingrid Dahlbom and Terri Daniels and Ester L{\"o}rinc and Sten Anders Ivarsson and {\AA}ke Lernmark and T. H. Hansson},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2005},
  volume={41 3},
  pages={
          322-7
        }
}
OBJECTIVES The conformation of tissue transglutaminase might influence the performance of immunoassays to detect autoantibodies from patients with celiac disease. The present study investigated how the exposure of tissue transglutaminase kept in a liquid phase and fixed to a solid support affected the binding of immunoglobulin (Ig)A and IgG autoantibodies in children with untreated and treated celiac disease. METHODS Included were 73 untreated celiac disease children, 50 controls and 80… CONTINUE READING