Autoantibodies against inosine-5'-monophosphate dehydrogenase 2--characteristics and prevalence in patients with HCV-infection.

@article{Seelig2011AutoantibodiesAI,
  title={Autoantibodies against inosine-5'-monophosphate dehydrogenase 2--characteristics and prevalence in patients with HCV-infection.},
  author={H P Seelig and Heribert Appelhans and Oliver Bauer and Martin Bl{\"u}thner and K. Hartung and Peter Schranz and Detlev Schultze and Claudia A Seelig and Martin Volkmann},
  journal={Clinical laboratory},
  year={2011},
  volume={57 9-10},
  pages={753-65}
}
BACKGROUND Indirect immunofluorescence (IIFT) on in house HEp-2 cell preparations revealed a novel antibody giving a granular cytoplasmic pattern not described before, which on two commercial cell preparations revealed a "rings and rods" pattern. This pattern was also observed in four HCV-RNA carriers and prompted the identification of the reactive antigen and the evaluation of the antibody prevalence in HCV-RNA carriers and control groups. METHODS The antigen's molecular weight was… CONTINUE READING
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Identification of Inosine-1,2-monophosphate dehydrogenase as a novel autoantigen

  • M Blüthner, H Appelhans, I Moosbrugger, C Wiemann, D Lenz, H.-P. Seelig
  • Report on the 9th Dresden Symposium on…
  • 2009
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