Autoantibodies against granulocyte colony-stimulating factor in Felty's syndrome and neutropenic systemic lupus erythematosus.

@article{Hellmich2002AutoantibodiesAG,
  title={Autoantibodies against granulocyte colony-stimulating factor in Felty's syndrome and neutropenic systemic lupus erythematosus.},
  author={Bernhard Hellmich and Elena Csernok and Helmut Schatz and Wolfgang Ludwig Gross and Armin Schnabel},
  journal={Arthritis and rheumatism},
  year={2002},
  volume={46 9},
  pages={2384-91}
}
OBJECTIVE Cytokines and growth factors can be a target of autoantibodies in systemic inflammatory diseases. We examined whether patients with neutropenia and either Felty's syndrome (FS) or systemic lupus erythematosus (SLE) have autoantibodies against granulocyte colony-stimulating factor (G-CSF) and whether these autoantibodies are functionally relevant. METHODS Fifteen patients with neutropenia due to FS were matched for age, sex, and disease activity with 16 normocytic rheumatoid… CONTINUE READING
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