Autoantibodies against aquaporin-4 in patients with neuropsychiatric systemic lupus erythematosus and primary Sjögren's syndrome.

@article{Wandinger2010AutoantibodiesAA,
  title={Autoantibodies against aquaporin-4 in patients with neuropsychiatric systemic lupus erythematosus and primary Sj{\"o}gren's syndrome.},
  author={Klaus Peter Wandinger and Martin Stangel and Torsten Witte and Patrick J W Venables and Peter J. Charles and Sven Jarius and Brigitte T. Wildemann and Christian Probst and Christof Iking-Konert and Matthias Schneider},
  journal={Arthritis and rheumatism},
  year={2010},
  volume={62 4},
  pages={1198-200}
}
Neurologic manifestations occur in up to 70% of patients with systemic lupus erythematosus (SLE) and in 20% of patients with Sjögren’s syndrome (SS) and are associated with significant morbidity. There is as yet no biologic marker that specifically indicates neurologic involvement in rheumatic diseases. In the literature to date, the association between nervous system manifestations of SLE and autoantibodies against ribosomal P proteins and N-methyl-Daspartate receptor has been inconsistently… CONTINUE READING

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