Autoantibodies against alpha B-crystallin, a candidate autoantigen in multiple sclerosis, are part of a normal human immune repertoire.

@article{Noort2006AutoantibodiesAA,
  title={Autoantibodies against alpha B-crystallin, a candidate autoantigen in multiple sclerosis, are part of a normal human immune repertoire.},
  author={Johannes M. van Noort and Richard Verbeek and Jan F. Meilof and Christoph H Polman and Sandra Amor},
  journal={Multiple sclerosis},
  year={2006},
  volume={12 3},
  pages={287-93}
}
Human T-cell responses to the stress protein alpha B-crystallin in multiple sclerosis (MS)-affected brain samples are dominant when compared to other myelin antigens. The establishment of the apparent autoimmune repertoire against this antigen has been suggested to involve cross-priming during viral infection. Yet, another possibility would be that… CONTINUE READING