Autoantibodies after bone marrow transplantation in children with genetic disorders: relation to chronic graft-versus-host disease.

@article{Lortan1992AutoantibodiesAB,
  title={Autoantibodies after bone marrow transplantation in children with genetic disorders: relation to chronic graft-versus-host disease.},
  author={J. E. Lortan and N C Rochfort and M el-Tumi and Ashok Vellodi},
  journal={Bone marrow transplantation},
  year={1992},
  volume={9 5},
  pages={
          325-30
        }
}
The occurrence of autoantibodies and their relation to chronic graft-versus-host disease (GVHD) have been studied in children, 100 days or more following allogenic bone marrow transplantation (BMT), mainly performed for a variety of genetic disorder. Seventeen of 40 patients had autoantibodies to thyroid microsomes, compared with none of 46 control children of similar age (p less than 0.001). The presence of these antibodies was strongly associated with chronic GVHD (14 of 20 patients), p = 0… CONTINUE READING