Autoantibodies Against Modified Low Density Lipoprotein Noniipid Factor of Blood Plasma That Stimulates Foam Cell Formation

The blood serum of patients with coronary atherosclerosis possesses an ability to induce the accumulation of cellular lipids in primary cultures of human aortic intimal cells. Factors responsible for this property of the atherosclerotic patients' sera are represented by modified (desialylated) low density lipoprotein (LDL) and a noniipid factor interacting… (More)