Autoamplification‐Enhanced Oxidative Kinetic Resolution of sec‐Alcohols and Alkyl Mandelates, and its Kinetic Model

  title={Autoamplification‐Enhanced Oxidative Kinetic Resolution of sec‐Alcohols and Alkyl Mandelates, and its Kinetic Model},
  author={Evgenii P. Talsi and Konstantin P. Bryliakov},
In this contribution, the new dynamic nonlinear effect in asymmetric catalysis is discussed, manifesting itself in the oxidative kinetic resolution (OKR) of racemic secondary benzylic alcohols and alkyl mandelates with H2O2 in the presence of chiral Mn‐based catalyst, with the apparent selectivity factor (krel) of the resolution being nonconstant over the reaction course. Typically, the initial growth of krel is changed into decay at high conversions. In this contribution, we demonstrate the… 
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