Autoallergy: a pathogenetic factor in atopic dermatitis?

  title={Autoallergy: a pathogenetic factor in atopic dermatitis?},
  author={Rudolf Valenta and Susanne Seiberler and Susanne Natter and Vera Mahler and Roschanak Mossabeb and Johannes Ring and Georg Stingl},
  journal={The Journal of allergy and clinical immunology},
  volume={105 3},
Long before the discovery of IgE it was reported that human dander extract can elicit immediate-type skin reactions in patients with severe atopy and that this skin sensitivity can be passively transferred with serum. Several recent findings have rekindled the interest in this phenomenon and led to the concept that IgE autoreactivity may play a pathogenetic role in severe and chronic forms of atopy. The elucidation of the nature of several environmental allergens has revealed striking… CONTINUE READING

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