Autoactivation of Xenopus Thyroid Hormone Receptor beta Genes Correlates with Larval Epithelial Apoptosis and Adult Cell Proliferation.

@article{Shi1997AutoactivationOX,
  title={Autoactivation of Xenopus Thyroid Hormone Receptor beta Genes Correlates with Larval Epithelial Apoptosis and Adult Cell Proliferation.},
  author={Y.-B. Shi and Atsuko Ishizuya-Oka},
  journal={Journal of biomedical science},
  year={1997},
  volume={4 1},
  pages={9-18}
}
The thyroid hormone (T(3))-dependent amphibian metamorphosis involves degeneration of larval tissues through programmed cell death (apoptosis) and concurrent proliferation and differentiation of adult cell types. As the mediators of the causative effects of T(3) on metamorphosis, both thyroid hormone receptor (TR) alpha and beta genes have been found to be expressed in different tissues during this process. In particular, the Xenopus TRbeta genes have been shown to be regulated by T(3) at the… CONTINUE READING

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