Auto‐transplantation of the uterus in the domestic pig (Sus scrofa): Surgical technique and early reperfusion events

@article{Wranning2006AutotransplantationOT,
  title={Auto‐transplantation of the uterus in the domestic pig (Sus scrofa): Surgical technique and early reperfusion events},
  author={Caiza Alm{\'e}n Wranning and Randa Racho El-Akouri and Cecilia Lundmark and Pernilla Dahm-K{\"a}hler and Johan M{\"o}lne and Anders Enskog and Mats Br{\"a}nnstr{\"o}m},
  journal={Journal of Obstetrics and Gynaecology Research},
  year={2006},
  volume={32}
}
Aim:  To develop a method for auto‐transplantation of the uterus in the pig and to evaluate the early reperfusion events after short‐term cold ischemia. 
Transplantation of the uterus in sheep: Methodology and early reperfusion events
TLDR
This study developed and evaluated autotransplantation of the sheep uterus to an orthotopic position in the pelvis and found it beneficial to use this model for research on uterine transplantation.
Test of long‐term uterine survival after allogeneic transplantation in rabbits
  • S. Saso, S. Hurst, +11 authors J Richard Smith
  • Medicine
    The journal of obstetrics and gynaecology research
  • 2014
To see if: (i) a large vessel aortocaval vascular patch technique may bring about long‐term graft survival after allogeneic uterine transplantation (UTn) in a rabbit model; and (ii) fertility can be
Uterine transplantation: one human case followed by a decade of experimental research in animal models
TLDR
The results of these specific studies on surgical technique, ischaemia‐reperfusion injury, immunosuppression and fertility are discussed.
Uterus Transplantation: An Update and Preparations for Introduction in India
The clinical field of composite tissue transplantation now also includes uterus transplantation (UTx), a new type of quality-oflife enhancing and in this case also life-giving transplantation. The
First report on fertility after allogeneic uterus transplantation
TLDR
For the first time pregnancy after allogeneic uterus transplantation is described, as a proof of concept of uterine function in a transplanted uterus in a standardized animal model (rat) under immunosuppression.
Uterus transplantation: Toward clinical application in Japan
In recent years, uterus transplantation (UTx) has been applied as the treatment for patients with uterine factor infertility worldwide. Thus, the clinical application of UTx in Japan should be
Uterus transplantation in the baboon: methodology and long-term function after auto-transplantation.
TLDR
This study demonstrates the feasibility of UTx by vascular anastomosis in a non-human primate species by developing surgical techniques for uterus retrieval and transplantation in the baboon.
Uterus Allo-Transplantation in a Swine Model: Long-Term Graft Survival and Reproductive Function
TLDR
This study evaluated the safety and feasibility of the technology of allogeneic UTx, which was performed only by transplant uterine artery system from living-donor surgery in a swine model to show long-term survival and resumed estrous after UTx.
Laparoscopic uterine graft procurement and surgical autotransplantation in ovine model
TLDR
The method used for laparoscopic live-donor ovariohysterectomy and graft harvest from a sheep model and an increase in the degree of fibrosis of the cervix samples in non-pregnant animals of the transplant group was noticed.
Sheep Model for Uterine Transplantation: The Best Option Before Starting a Human Program
TLDR
The success of four uterine auto-transplants in sheep models is described and all four animals were alive after the surgical procedure and were euthanized after the experimental period.
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