Autistic spectrum disorders and mitochondrial encephalopathies

@article{Holtzman2008AutisticSD,
  title={Autistic spectrum disorders and mitochondrial encephalopathies},
  author={David Holtzman},
  journal={Acta P{\ae}diatrica},
  year={2008},
  volume={97}
}
  • D. Holtzman
  • Published 1 July 2008
  • Medicine, Psychology, Biology
  • Acta Pædiatrica
Autistic spectrum disorders (ASD) are common neurobehavioral syndromes characterized by deficits in social interactions, impaired communication skills and repetitive stereotypic behaviours expressed by 3 years of age (1). Recent studies of these disorders indicate a strong genetic component but specific aetiologies and pathogeneses are usually unknown (1–3). Concordance for ASD is 90% in identical twins compared to 10% for dizygotic twins and siblings. In recent years the incidence of ASD has… 
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