Autism genetics

  title={Autism genetics},
  author={A. Persico and V. Napolioni},
  journal={Behavioural Brain Research},
  • A. Persico, V. Napolioni
  • Published 2013
  • Medicine
  • Behavioural Brain Research
  • Autism spectrum disorder (ASD) is a severe neuropsychiatric disease with strong genetic underpinnings. However, genetic contributions to autism are extremely heterogeneous, with many different loci underlying the disease to a different extent in different individuals. Moreover, the phenotypic expression (i.e., "penetrance") of these genetic components is also highly variable, ranging from fully penetrant point mutations to polygenic forms with multiple gene-gene and gene-environment… CONTINUE READING
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