Autism and serotonin transporter gene polymorphisms: A systematic review and meta‐analysis

@article{Huang2008AutismAS,
  title={Autism and serotonin transporter gene polymorphisms: A systematic review and meta‐analysis},
  author={C. H. Huang and S. Santangelo},
  journal={American Journal of Medical Genetics Part B: Neuropsychiatric Genetics},
  year={2008},
  volume={147B}
}
  • C. H. Huang, S. Santangelo
  • Published 2008
  • Biology, Medicine
  • American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
  • The serotonin transporter gene (5‐HTT) plays a crucial role in serotonergic neurotransmission and has been found to be associated, with varying degrees of significance, with many diseases, including autism. Prior association studies of autism have yielded conflicting results regarding the association between two common 5‐HTT polymorphisms, the promoter insertion/deletion (5‐HTTLPR) and the intron 2 VNTR (STin2 VNTR). We conducted a systematic review and meta‐analysis to test the following… CONTINUE READING
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