Autism and Intellectual Disability-Associated KIRREL3 Interacts with Neuronal Proteins MAP1B and MYO16 with Potential Roles in Neurodevelopment

@inproceedings{Liu2015AutismAI,
  title={Autism and Intellectual Disability-Associated KIRREL3 Interacts with Neuronal Proteins MAP1B and MYO16 with Potential Roles in Neurodevelopment},
  author={Ying Fu Liu and Sarah M. Sowell and Y. J. Luo and Alka Chaubey and Richard S. Cameron and Hyung-Goo Kim and Anand K. Srivastava},
  booktitle={PloS one},
  year={2015}
}
Cell-adhesion molecules of the immunoglobulin superfamily play critical roles in brain development, as well as in maintaining synaptic plasticity, the dysfunction of which is known to cause cognitive impairment. Recently dysfunction of KIRREL3, a synaptic molecule of the immunoglobulin superfamily, has been implicated in several neurodevelopmental conditions including intellectual disability, autism spectrum disorder, and in the neurocognitive delay associated with Jacobsen syndrome. However… CONTINUE READING
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