Aurora Kinase A Regulates M1 Macrophage Polarization and Plays a Role in Experimental Autoimmune Encephalomyelitis

Abstract

Macrophage polarization is a dynamic and integral process of tissue inflammation and remodeling. Here we demonstrate an important role of Aurora kinase A in the regulation of inflammatory M1 macrophage polarization. We found that there was an elevated expression of Aurora-A in M1 macrophages and inhibition of Aurora-A by small molecules or specific siRNA… (More)
DOI: 10.1007/s10753-014-9990-2

Topics

6 Figures and Tables

Statistics

05010015020162017
Citations per Year

Citation Velocity: 28

Averaging 28 citations per year over the last 2 years.

Learn more about how we calculate this metric in our FAQ.

Cite this paper

@article{Ding2014AuroraKA, title={Aurora Kinase A Regulates M1 Macrophage Polarization and Plays a Role in Experimental Autoimmune Encephalomyelitis}, author={Lixia Ding and Haijuan Gu and Xiaoming Gao and Sidong Xiong and Biao Zheng}, journal={Inflammation}, year={2014}, volume={38}, pages={800-811} }