Auromomycin-induced DMA Damage and Repair in Human Leukemic Lymphoblasts ( CCRF-CEM Cells ) 1

@inproceedings{Samy2006AuromomycininducedDD,
  title={Auromomycin-induced DMA Damage and Repair in Human Leukemic Lymphoblasts ( CCRF-CEM Cells ) 1},
  author={T. S. Anantha Samy and Larry L Wellham and Awtar Krishan},
  year={2006}
}
An alkaline elution procedure was used to study the nature of DNA damage induced by auromomycin, an antitumor protein, in human leukemic lymphoblasts (CCRF-CEM cells). The filter elu tion of drug-treated cells at pH 12.2 and 9.6 showed induction of both single and double strand DNA breaks. The DNA strand scission activities were linear in relation to drug… CONTINUE READING