Augmented serum level of major histocompatibility complex class I-related chain A (MICA) protein and reduced NKG2D expression on NK and T cells in patients with cervical cancer and precursor lesions

@article{ArreygueGarcia2007AugmentedSL,
  title={Augmented serum level of major histocompatibility complex class I-related chain A (MICA) protein and reduced NKG2D expression on NK and T cells in patients with cervical cancer and precursor lesions},
  author={Naela A. Arreygue-Garcia and Adri{\'a}n Daneri-Navarro and Alicia del Toro-Arreola and {\'A}ngel Cid-Arregui and Oscar Gonzalez-Ramella and Luis Felipe Jave-Suarez and Adriana Aguilar-Lemarroy and Rogelio Troyo-Sanrom{\'a}n and Alejandro Bravo-Cu{\'e}llar and Vidal Delgado-Rizo and Trinidad Garc{\'i}a-Iglesias and Georgina Hern{\'a}ndez-Flores and Susana del Toro-Arreola},
  journal={BMC Cancer},
  year={2007},
  volume={8},
  pages={16 - 16}
}
Cervical cancer is the second most common cancer in women worldwide. NK and cytotoxic T cells play an important role in the elimination of virus-infected and tumor cells through NKG2D activating receptors, which can promote the lysis of target cells by binding to the major histocompatibility complex class I-related chain A (MICA) proteins. Increased serum levels of MICA have been found in patients with epithelial tumors. The aim of this study was to compare the levels of soluble MICA (sMICA… CONTINUE READING
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Cervical cancer

  • DH Moore
  • Obstet Gynecol
  • 2006
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