Augmented Cardiac Hypertrophy in Response to Pressure Overload in Mice Lacking ELTD1

@inproceedings{Xiao2012AugmentedCH,
  title={Augmented Cardiac Hypertrophy in Response to Pressure Overload in Mice Lacking ELTD1},
  author={Jinfeng Xiao and Hong Jiang and Rui Zhang and Guangpu Fan and Yan Zhang and Dingsheng Jiang and Hongliang Li},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Epidermal growth factor (EGF), latrophilin and seven transmembrane domain-containing protein 1 (ELTD1) is developmentally upregulated in the heart. Little is known about the relationship between ELTD1 and cardiac diseases. Therefore, we aimed to clarify the role of ELTD1 in pressure overload-induced cardiac hypertrophy. METHODS AND RESULTS C57BL/6J wild-type (WT) mice and ELTD1-knockout (KO) mice were subjected to left ventricular pressure overload by descending aortic banding (AB… CONTINUE READING
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