Augmentation pressure is influenced by ventricular contractility/relaxation dynamics: novel mechanism of reduction of pulse pressure by nitrates.

@article{Fok2014AugmentationPI,
  title={Augmentation pressure is influenced by ventricular contractility/relaxation dynamics: novel mechanism of reduction of pulse pressure by nitrates.},
  author={Henry W Fok and A. Le Guilcher and Ye Li and Sally Emma Brett and Ajay Shah and Brian Clapp and Phil Chowienczyk},
  journal={Hypertension},
  year={2014},
  volume={63 5},
  pages={1050-5}
}
Augmentation pressure (AP), the increment in aortic pressure above its first systolic shoulder, is thought to be determined mainly by pressure wave reflection but could be influenced by ventricular ejection characteristics. We sought to determine the mechanism by which AP is selectively reduced by nitroglycerin (NTG). Simultaneous measurements of aortic pressure and flow were made at the time of cardiac catheterization in 30 subjects (11 women; age, 61±13 years [mean±SD]) to perform wave… CONTINUE READING
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Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis

C Vlachopoulos, K Aznaouridis, +3 authors K Stefanadis
Eur Heart J • 2010

An introduction to wave intensity analysis

Kh Parker
Med Biol Eng Comput • 2009

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