Augmentation of type I IL-1 receptor expression and IL-1 signaling by IL-6 and glucocorticoid in murine hepatocytes.

Abstract

IL-1 signal is transduced through type I receptor (IL-1RI). We have recently reported that LPS augments IL-1RI mRNA expression in the hepatocytes of mice in vivo, and the augmentation is mediated by the interaction of IL-1, IL-6, and glucocorticoid (GC). In this study, we examined whether IL-1RI mRNA expression level in the hepatocytes reflects those of… (More)

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@article{Ito1999AugmentationOT, title={Augmentation of type I IL-1 receptor expression and IL-1 signaling by IL-6 and glucocorticoid in murine hepatocytes.}, author={Akiko Ito and Takemasa Takii and Tomotake Matsumura and Kikuo Onozaki}, journal={Journal of immunology}, year={1999}, volume={162 7}, pages={4260-5} }