Augmentation of peritoneal dialysis clearance with procaine.

@article{Brborowicz1984AugmentationOP,
  title={Augmentation of peritoneal dialysis clearance with procaine.},
  author={Andrzej Bręborowicz and Jan Knapowski},
  journal={Kidney international},
  year={1984},
  volume={26 4},
  pages={
          392-6
        }
}
Local anesthetic procaine in a 0.25% concentration was used as the adjunct to the dialysis fluid during peritoneal dialysis in rabbits. Procaine increased peritoneal clearance of urea (2.213 +/- 0.187 ml/min to 3.544 +/- 0.41 ml/min) and inulin (0.528 +/- 0.079 ml/min to 0.852 +/- 0.213 ml/min). Effect of the drug persisted, despite its lack, during the following cycles. Procaine influenced transmesothelial transfer of urea and inulin in vitro. The effect of the drug was biphasic. During the… 
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Local Anesthetic -Bupiv Acaine Increases the Peritoneal Transport of Solutes. Part I: In Vivo Study
A local anesthetic -bupivacaine was used in concentration 0.25 mmol/l in the dialysis fluid during peritoneal dialysis in rabbits. Bupivacaine increased the mean peritoneal clearance of urea by 33%…
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    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
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The focus of this chapter will be to review the available information regarding peritoneal micro-circulatory function in relation toperitoneal dialysis by examining the following areas: the functional anatomy of the peritoneAL microcirculation, the physiologic factors modifying thePeritonealMicrocirculation and the role of the Peritoneal Microcirculation in inflammation.
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An experimental animal PD model established in nonuremic and uremic rats helps to understand the pathophysiology of PD but also can be used for testing biocompatibility of new PD fluids.
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The Textbook of Peritoneal Dialysis
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The Textbook of Peritoneal Dialysis is unique in its detailed discussion of a complete range of topics, including new advances in the authors' understanding of the physiology of peritoneal dialysis, peritoneAL dialysis kinetics, clinical results and a chapter dealing with the concepts of intraperitoneal chemotherapy.
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In this chapter we will review the nature of the dialysis solutions added to the peritoneal cavity, discuss concepts of intraperitoneal nutrition, and review the transport of antibiotics and other…
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The development of an adequate animal model for peritoneal research remains an object of concern because of the large variety of available models that make interpretation of results and comparison of studies very difficult.
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