Augmentation of human K-cell activity with interferon.

  title={Augmentation of human K-cell activity with interferon.},
  author={John R. Ortaldo and Sidney Pestka and R Bradley Slease and Menachem Rubinstein and Ronald B. Herberman},
  journal={Scandinavian journal of immunology},
  volume={12 5},
Our laboratory recently reported that interferon (IF) could augment human antibody-dependent cellular cytotoxicity (ADCC) and cytotoxicity by natural killer (NK) cells. Although there is general agreement that IF can boost the activity of human NK cells, two laboratories have reported a failure to boost ADCC. We have therefore examined in more detail the… CONTINUE READING