Augmentation of endothelial function following exercise training is associated with increased L-arginine transport in human heart failure.

@article{Parnell2005AugmentationOE,
  title={Augmentation of endothelial function following exercise training is associated with increased L-arginine transport in human heart failure.},
  author={Melinda M Parnell and Diane P Holst and David M. Kaye},
  journal={Clinical science},
  year={2005},
  volume={109 6},
  pages={523-30}
}
We have reported previously a decrease in the clearance of the NO (nitric oxide) precursor L-arginine in the forearm circulation of CHF (congestive heart failure) patients, suggesting a potential rate-limiting mechanism contributing to the common finding of endothelial dysfunction in CHF. Given data that show exercise training augments endothelial function in CHF, the aim of the present study was to investigate whether these improvements were due to an increase in L-arginine transport. Measures… CONTINUE READING

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Asymmetric dimethylarginine: an endogenous inhibitor of nitric oxide synthesis in chronic heart failure: effects of exercise training

  • J. Niebauer, R. H. Boger, K. M. Webb-Peploe
  • Circulation 104,
  • 2001

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