Augmentation effect of combination therapy of aripiprazole and antidepressants on forced swimming test in mice

@article{Bourin2009AugmentationEO,
  title={Augmentation effect of combination therapy of aripiprazole and antidepressants on forced swimming test in mice},
  author={Michel S Bourin and Franck Chenu and Corina M Prica and Martine Hasc{\"o}et},
  journal={Psychopharmacology},
  year={2009},
  volume={206},
  pages={97-107}
}
A deficiency in brain monoamine systems (serotonin, dopamine, and/or norepinephrine) have long been hypothesized for the pathogenesis of depression. Drugs enhancing neurotransmission of those monoamines have been proven to have antidepressant effects. We hypothesized that aripiprazole, a partial D2 agonist, could increase the activity of various… CONTINUE READING