Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings

@article{Waldo1994AuditorySG,
  title={Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings},
  author={Merilyne C. Waldo and Ellen M Cawthra and Lawrence E. Adler and Sherry Dubester and Michael P. Staunton and Hisashi Nagamoto and Nettie Baker and Anna Madison and Jack Simon and Ann L. Scherzinger},
  journal={Schizophrenia Research},
  year={1994},
  volume={12},
  pages={93-106}
}
Schizophrenia may result from the concerted action of several pathophysiological factors. This pilot study compared the distribution of measurements of three such putative factors in 11 schizophrenics and their siblings: a neurophysiological deficit in auditory sensory gating, diminished hippocampal volume, and increased catecholamine metabolism. Abnormal auditory sensory gating was found in all schizophrenics in the 11 families studied and in 8 of their 20 siblings. Compared with the… CONTINUE READING
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