Auditory evoked response and awareness: a study in volunteers at sub-MAC concentrations of isoflurane.

  title={Auditory evoked response and awareness: a study in volunteers at sub-MAC concentrations of isoflurane.},
  author={D. E. Newton and Chad Thornton and K. M. Konieczko and C. R. Jordan and Nigel R. Webster and N. P. Luff and Christopher D. Frith and Caroline J. Dor{\'e}},
  journal={British journal of anaesthesia},
  volume={69 2},
We have investigated the relationship between the auditory evoked response (AER) and simple tests of conscious awareness at four end-expiratory concentrations (0.0, 0.1, 0.2 and 0.4 MAC) of isoflurane in oxygen in each of eight anaesthetist volunteers, in random order, at least 1 week apart. The early cortical AER was recorded from electrodes at the vertex and inion. Amplitudes of the waves Pa, Nb and Pc and latencies of the waves Na, Pa, Nb, Pb and Nc were measured. All the AER variables were… CONTINUE READING
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  • CJ, NR Webster, NP. Luff
  • British Journal of Anaesthesia
  • 1990
Highly Influential
4 Excerpts

Assessment of Graded Changes in the Central Nervous System During General Anaesthesia and Surgery in Man, Using the Auditory Evoked Response

  • C. Thornton
  • Ph.D. Thesis. London: University of London,
  • 1990
2 Excerpts