Auditory Hallucinations in Schizophrenia Are Associated with Reduced Functional Connectivity of the Temporo-Parietal Area

@article{Vercammen2010AuditoryHI,
  title={Auditory Hallucinations in Schizophrenia Are Associated with Reduced Functional Connectivity of the Temporo-Parietal Area},
  author={Ans Vercammen and Henderikus Knegtering and J. A. den Boer and Edith Jantine Liemburg and Andr{\'e} Aleman},
  journal={Biological Psychiatry},
  year={2010},
  volume={67},
  pages={912-918}
}
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216 Citations

Resting State Functional Connectivity in Patients with Chronic Hallucinations
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Compared resting state connectivity between psychotic patients with chronic AVH and matched controls is compared to identify functional brain systems underlying the predisposition to hallucinate, and aberrant connectivity between the seed regions and medial temporal lobe structures which have a prominent role in memory retrieval is found.
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The findings indicate that disrupted intrinsic connectivity of a speech-related network could underlie persistent AVHs in patients with schizophrenia, and the occurrence of hallucinatory symptoms seems to modulate RSNs associated with attention and executive control.
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Resting-state functional connectivity in medication-naïve schizophrenia patients with and without auditory verbal hallucinations: A preliminary report
Auditory Verbal Hallucinations and Brain Dysconnectivity in the Perisylvian Language Network: A Multimodal Investigation
TLDR
Findings seem to suggest that, in the early stage of the disorder, a significant impairment of fronto-temporal connectivity is evident in patients who do not experience AVHs, consistent with the hypothesis that more severe alterations may prevent the occurrence of the hallucinatory experience.
schizophrenia patients with persistent auditory verbal hallucinations
TLDR
The results suggest cross-network abnormalities between DN and salience system in patients with persistent hallucinations may be connected to schizophrenia.
Aberrant resting-state connectivity in non-psychotic individuals with auditory hallucinations
TLDR
Aberrant connectivity of frontal, parahippocampal and superior temporal brain areas can be specifically related to the predisposition to hallucinate in the auditory domain.
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