Atypical multiple system atrophy is a new subtype of frontotemporal lobar degeneration: frontotemporal lobar degeneration associated with α-synuclein

@article{Aoki2015AtypicalMS,
  title={Atypical multiple system atrophy is a new subtype of frontotemporal lobar degeneration: frontotemporal lobar degeneration associated with α-synuclein},
  author={Naoya Aoki and Philip Boyer and Cheryl Lund and Wen-lang Lin and Shunsuke Koga and Owen A. Ross and Myron Weiner and Anne Lipton and J Michael Powers and Charles L. White and Dennis W. Dickson},
  journal={Acta Neuropathologica},
  year={2015},
  volume={130},
  pages={93-105}
}
Multiple system atrophy (MSA) is a sporadic neurodegenerative disease clinically characterized by cerebellar signs, parkinsonism, and autonomic dysfunction. Pathologically, MSA is an α-synucleinopathy affecting striatonigral and olivopontocerebellar systems, while neocortical and limbic involvement is usually minimal. In this study, we describe four patients with atypical MSA with clinical features consistent with frontotemporal dementia (FTD), including two with corticobasal syndrome, one with… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision Medicine

International journal of molecular sciences • 2016
View 17 Excerpts
Highly Influenced

Dilemma of multiple system atrophy and spinocerebellar ataxias

Journal of Neurology • 2018
View 1 Excerpt

Multiple System Atrophy: An Oligodendroglioneural Synucleinopathy1

Journal of Alzheimer's disease : JAD • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 48 references

The definition of multiple system atrophy: a review of recent developments.

Journal of neuropathology and experimental neurology • 1998
View 15 Excerpts
Highly Influenced

Frontotemporal dementia. In: Rosenberg RN, Padcual JM (eds) Rosenberg’s molecular and genetic basis of neurological and psychiatric disease

S Shinagawa, B Miller
5th edn. Elsevier, • 2015
View 9 Excerpts
Highly Influenced

Primary progressive aphasia: clinicopathological correlations

Nature Reviews Neurology • 2010
View 4 Excerpts
Highly Influenced

Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy.

Journal of neurology, neurosurgery, and psychiatry • 1969
View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…