Atypical hemolytic uremic syndrome

@inproceedings{Loirat2011AtypicalHU,
  title={Atypical hemolytic uremic syndrome},
  author={Chantal Loirat and V{\'e}ronique Fr{\'e}meaux-Bacchi},
  booktitle={Orphanet journal of rare diseases},
  year={2011}
}
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae or other causes, aHUS designates a primary disease due to a disorder in complement alternative pathway regulation. Atypical HUS represents 5 -10% of HUS in children, but the majority of HUS in adults. The incidence of complement-aHUS is not… CONTINUE READING
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