Atypical form of active melorheostosis and its treatment with bisphosphonate

@article{Donath2002AtypicalFO,
  title={Atypical form of active melorheostosis and its treatment with bisphosphonate},
  author={J. W. F. Donath and Gyula Po{\'o}r and Csaba Akos Kiss and B{\'e}la Fornet and Harry Genant},
  journal={Skeletal Radiology},
  year={2002},
  volume={31},
  pages={709-713}
}
We present the case of a 38-year-old man in whom extensive bilateral melorheostosis was associated with elevated serum alkaline phosphatase, swelling of the right foot and progressive deformity of the left hand, left leg and right foot. Radiography, computed tomography and bone scintigraphy were performed. Following treatment with bisphosphonate (30 mg/day of pamidronate for 6 days) infusion, the pain and swelling of his right foot showed improvement and his elevated serum alkaline phosphatase… CONTINUE READING