Atypical extraventricular neurocytoma with oligodendroglioma-like spread and an unusual pattern of chromosome 1p and 19q loss.

@article{Mrak2004AtypicalEN,
  title={Atypical extraventricular neurocytoma with oligodendroglioma-like spread and an unusual pattern of chromosome 1p and 19q loss.},
  author={Robert E. Mrak and M. Gazi Yaşargil and Gayatry Mohapatra and James K. Earel and David N Louis},
  journal={Human pathology},
  year={2004},
  volume={35 9},
  pages={1156-9}
}
An insular cortex tumor in a 54-year-old woman showed unequivocal neurocytic features, including open nuclei, distinct nucleoli, and strong synaptophysin immunoreactivity. Ultrastructurally, there were neuritic-type processes with microtubules and hillock-like attachments, and there were dense-core granules. Atypical features were mitotic activity, prominent vasculature, and small foci of necrosis. Peripherally, there was oligodendroglia-like histology with single-cell infiltration of white… CONTINUE READING

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