Atypical clinical presentation of a subset of patients with anti-RNA polymerase III - non-scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining

@inproceedings{Ceribelli2011AtypicalCP,
  title={Atypical clinical presentation of a subset of patients with anti-RNA polymerase III - non-scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining},
  author={Angela Ceribelli and Malgorzata E. Krzyszczak and Yi Li and Steven J. Ross and Jason Y F Chan and Edward K L Chan and Rufus Watson Burlingame and Tyler T Webb and Michael R. Bubb and Eric S. Sobel and Westley H. Reeves and Minoru Satoh},
  booktitle={Arthritis research & therapy},
  year={2011}
}
INTRODUCTION Anti-RNA polymerase III (RNAP III) antibodies are highly specific markers of scleroderma (systemic sclerosis, SSc) and associated with a rapidly progressing subset of SSc. The clinical presentation of anti-RNAP III positive patients, onset of Raynaud's phenomenon (RP) and SSc in unselected patients in a rheumatology clinic were evaluated. METHODS Autoantibodies in sera from 1,966 unselected patients (including 434 systemic lupus erythematosus (SLE), 119 SSc, 85 polymyositis… CONTINUE READING

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