Atypical antipsychotics do not reverse prepulse inhibition deficits in acutely psychotic schizophrenia.

@article{Xue2012AtypicalAD,
  title={Atypical antipsychotics do not reverse prepulse inhibition deficits in acutely psychotic schizophrenia.},
  author={Y-Y Xue and H-N Wang and Fubo Xue and Q Tan},
  journal={The Journal of international medical research},
  year={2012},
  volume={40 4},
  pages={1467-75}
}
OBJECTIVES To investigate the effects of atypical antipsychotics on prepulse inhibition, startle response and habituation in acutely psychotic patients with schizophrenia, and investigate whether prepulse inhibition deficit improvements are a result of the direct impact of atypical antipsychotics or improvements in antipsychotic-related symptoms. METHODS Prepulse inhibition, habituation and acoustic startle response were evaluated in healthy control subjects and patients with schizophrenia… CONTINUE READING
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Disruption of prepulse

  • G Le Pen, JL Moreau
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