Attributable risks of familial cancer from the Family-Cancer Database.

@article{Hemminki2002AttributableRO,
  title={Attributable risks of familial cancer from the Family-Cancer Database.},
  author={Kari Hemminki and Kamila Czene},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2002},
  volume={11 12},
  pages={
          1638-44
        }
}
Population attributable faction (PAF) shows the proportion of the disease that could be prevented if the cause could be removed. PAFs for most types of familial cancer have not been determined. We used the Swedish Family-Cancer Database on 10.2 million individuals and 688,537 parental and 116,741 offspring cancers to calculate familial risks, proportions of affected individuals, and familial PAFs for 28 neoplasms among 0-66-year-old offspring. The data were calculated by an exact proband status… CONTINUE READING

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Correspondence re: Risch, N.: Genetic epidemiology of cancer: interpreting family and twin studies and their implications for molecular genetic approaches. Cancer Epidemiol. Biomark. Prev., 10: 733-741, 2001.

  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • 2002

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