Attractin: a cub-family protease involved in T cell-monocyte/macrophage interactions.

  title={Attractin: a cub-family protease involved in T cell-monocyte/macrophage interactions.},
  author={Jonathan S Duke-Cohan and W Tang and Stuart F. Schlossman},
  journal={Advances in experimental medicine and biology},
Attractin is a rapidly upregulated membrane-associated molecule on activated T cells. It is a member of the CUB family of extracellular guidance and development proteins, sharing with them a protease activity similar to that of Dipeptidyl peptidase IV (DPPIV/CD26). Most remarkably, and in sharp contrast to CD26, it is released from the T cell and is presumed to be a major source of a soluble serum-circulating attractin. Genomic sequencing reveals that the soluble form is not a proteolytic… CONTINUE READING
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