Attenuation of ureteral obstruction-induced renal injury by polyenylphosphatidylcholine.

  title={Attenuation of ureteral obstruction-induced renal injury by polyenylphosphatidylcholine.},
  author={Melih Akin and Savaş Demirbilek and Selma Ay and Kubilay Gurunluoglu and Emine Turkmen and Erkan Taş and Rauf Tuğrul Aksoy and Aysun Baykarabulut and Mehmet Naci Edali},
  journal={International journal of urology : official journal of the Japanese Urological Association},
  volume={14 4},
BACKGROUND The cytoprotective, antioxidant and antifibrotic effects of polyenylphosphatidylcholine (lecithin, PPC) have been demonstrated both experimentally and clinically. The present study investigated whether PPC treatment has any beneficial effect on renal injury in unilateral partial ureteral obstruction (UUO) in rats. METHODS Forty Wistar-Albino rats were split into three groups (sham-operated controls, untreated and treated rats). Rats of the untreated and treated groups (n = 15… CONTINUE READING


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