Attenuation of the effects of cocaine on milk consumption in rats by dopamine antagonists

  title={Attenuation of the effects of cocaine on milk consumption in rats by dopamine antagonists},
  author={D. Rapoza and W. Woolverton},
  journal={Pharmacology Biochemistry and Behavior},
  • D. Rapoza, W. Woolverton
  • Published 1991
  • Medicine
  • Pharmacology Biochemistry and Behavior
  • Recent research suggest the both D1 and D2 dopamine (DA) receptors play an important role in the behavioral effects of psychomotor stimulants. The present study utilized selective DA antagonists to examine the role of DA receptors in the effects of cocaine on milk intake in rats. Male Sprague-Dawley rats were given access to a milk solution (2:1 tap water:Bordens sweetened condensed milk) for 15 min each day. When milk intake was stable, dose-response functions were determined for cocaine (4.0… CONTINUE READING
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