Attenuation of oxidative and nitrosative stress in cortical area associates with antidepressant-like effects of tropisetron in male mice following social isolation stress

@article{HajMirzaian2016AttenuationOO,
  title={Attenuation of oxidative and nitrosative stress in cortical area associates with antidepressant-like effects of tropisetron in male mice following social isolation stress},
  author={A. Haj‐Mirzaian and S. Amiri and Hossein Amini-Khoei and M. Rahimi-Balaei and S. E. Mehr},
  journal={Brain Research Bulletin},
  year={2016},
  volume={124},
  pages={150-163}
}
Tropisetron, a 5-HT3 receptor antagonist widely used as an antiemetic, has been reported to have positive effects on mood disorders. Adolescence is a critical period during the development of brain, where exposure to chronic stress during this time is highly associated with the development of depression. In this study, we showed that 4 weeks of juvenile social isolation stress (SIS) provoked depressive-like behaviors in male mice, which was associated with disruption of mitochondrial function… Expand
View on Elsevier
eprints.skums.ac.ir
32 Citations
Highly Influential Citations
1
Background Citations
8
Methods Citations
2

32 Citations

Citation Type

Citation Type

Minocycline attenuates depressive-like behaviors in mice treated with the low dose of intracerebroventricular streptozotocin; the role of mitochondrial function and neuroinflammation
Blockade of nitric oxide signalling promotes resilience to the effects of social defeat stress on the conditioned rewarding properties of MDMA in mice.
  • 1
Exercise During Adolescence Attenuated Depressive-Like Behaviors and Hippocampal Mitochondrial Dysfunction Following Early Life Stress in Adult Male Rats
  • 3
  • PDF
Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal
  • 12
Oxytocin mitigated the depressive-like behaviors of maternal separation stress through modulating mitochondrial function and neuroinflammation
  • 59
  • PDF
Involvement of opioid system in behavioral despair induced by social isolation stress in mice.
  • 5
Chronic Isolation Stress Affects Subsequent Crowding Stress-Induced Brain Nitric Oxide Synthase (NOS) Isoforms and Hypothalamic-Pituitary-Adrenal (HPA) Axis Responses
  • 7
  • PDF
The effect of tropisetron on oxidative stress, SIRT1, FOXO3a, and claudin-1 in the renal tissue of STZ-induced diabetic rats
  • 1
Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine‐to‐glutamate ratio and myo‐inositol concentration in the mouse frontal cortex
  • 9
  • PDF
Neurobiology and consequences of social isolation stress in animal model-A comprehensive review.
  • 61
...
1
2
3
4
...

References

SHOWING 1-10 OF 78 REFERENCES
Tropisetron attenuated the anxiogenic effects of social isolation by modulating nitrergic system and mitochondrial function.
  • 32
Involvement of the nitrergic system in the proconvulsant effect of social isolation stress in male mice
  • 23
  • PDF
Inducible nitric oxide synthase is involved in the modulation of depressive behaviors induced by unpredictable chronic mild stress
  • 87
The Effects of Antidepressant Treatment in Prenatally Stressed Rats Support the Glutamatergic Hypothesis of Stress-Related Disorders
  • 74
  • PDF
Blockade of NMDA receptors reverses the depressant, but not anxiogenic effect of adolescence social isolation in mice.
  • 43
Co-occurrence of anxiety and depressive-like behaviors following adolescent social isolation in male mice; possible role of nitrergic system
  • 67
Elevated level of nitric oxide mediates the anti-depressant effect of rubidium chloride in mice.
  • 48
Inhibition of iNOS induces antidepressant-like effects in mice: Pharmacological and genetic evidence
  • 67
Different susceptibility of prefrontal cortex and hippocampus to oxidative stress following chronic social isolation stress
  • 71
Effects of the selective nonpeptide corticotropin-releasing factor receptor 1 antagonist antalarmin in the chronic mild stress model of depression in mice
  • 192
  • PDF
...
1
2
3
4
5
...