Attenuation of monocyte chemotaxis--a novel anti-inflammatory mechanism of action for the cardio-protective hormone B-type natriuretic peptide.

@article{Glezeva2013AttenuationOM,
  title={Attenuation of monocyte chemotaxis--a novel anti-inflammatory mechanism of action for the cardio-protective hormone B-type natriuretic peptide.},
  author={Nadezhda Glezeva and Patrick Collier and Victor Voon and Mark Thomas Ledwidge and Kenneth M. McDonald and Christopher J E Watson and John A. Baugh},
  journal={Journal of cardiovascular translational research},
  year={2013},
  volume={6 4},
  pages={545-57}
}
B-type natriuretic peptide (BNP) is a prognostic and diagnostic marker for heart failure (HF). An anti-inflammatory, cardio-protective role for BNP was proposed. In cardiovascular diseases including pressure overload-induced HF, perivascular inflammation and cardiac fibrosis are, in part, mediated by monocyte chemoattractant protein (MCP)1-driven monocyte migration. We aimed to determine the role of BNP in monocyte motility to MCP1. A functional BNP receptor, natriuretic peptide receptor-A… CONTINUE READING

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interactions with 556 J

  • B. K. Huntley, S. M. Sandberg, +4 authors et al. . BNP-induced activation of cGMP in human card fibroblasts
  • of Cardiovasc. Trans. Res.
  • 2013
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