Attenuation of monocrotaline-induced pulmonary arterial hypertension in rats by rosuvastatin.


BACKGROUND Although the effects of statins on pulmonary arterial hypertension (PAH) have been studied previously, the results remain uncertain. OBJECTIVE The aim of this study was to confirm the impacts of rosuvastatin on monocrotaline (MCT)-induced PAH and potential mechanisms. METHODS Rats were subjected to a single subcutaneous injection of MCT to… (More)
DOI: 10.1097/FJC.0b013e31825cce63