Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus.

Abstract

The antiviral neuraminidase inhibitor oseltamivir (OSV) is widely used to suppress viral replication in the treatment of influenza. Here, we report that OSV administration significantly suppressed respiratory mucosal secretory IgA responses with respect to antigen (Ag)-specific antibody (Ab) production and also the induction of Ag-specific IgA Ab-forming… (More)
DOI: 10.1016/j.micinf.2010.04.013

Topics

  • Presentations referencing similar topics